Selected Publications
Authored by UF Health Cancer Center Members | 2020
*UF Health Cancer Center affiliates in bold.

Chulanetra M, Morchang A, Sayour E, Eldjerou L, Milner R, Lagmay J, Cascio M, Stover B, Slayton W, Chaicumpa W, Yenchitsomanus PT, Chang LJ. GD2 chimeric antigen receptor modified T cells in synergy with sub-toxic level of doxorubicin targeting osteosarcomas. Am J Cancer Res. 2020 Feb 1;10(2):674-687. eCollection 2020. PubMed PMID: 32195035; PubMed Central PMCID: PMC7061749.
Salloum RG, Lee J, Lee JH, Boeckmann M, Xing C, Warren GW. Smoking-Cessation Methods and Outcomes Among Cancer Survivors. Am J Prev Med. 2020 Oct;59(4):615-617. doi: 10.1016/j.amepre.2020.03.016. Epub 2020 May 21. PubMed PMID: 32446750.
Farhadfar N, Kelly DL, Mead L, Nair S, Colee J, Irizarry Gatell V, Murthy HS, Brown RA, Hiemenz JW, Hsu JW, May WS, Wingard JR, Dahl WJ. Dietary Intake and Diet Quality of Hematopoietic Stem Cell Transplantation Survivors. Biol Blood Marrow Transplant. 2020 Jun;26(6):1154-1159. doi: 10.1016/j.bbmt.2020.02.017. Epub 2020 Feb 24. PubMed PMID: 32105830; PubMed Central PMCID: PMC7271096.
Murthy HS, Gharaibeh RZ, Al-Mansour Z, Kozlov A, Trikha G, Newsome RC, Gauthier J, Farhadfar N, Wang Y, Kelly DL, Lybarger J, Jobin C, Wang GP, Wingard JR. Baseline Gut Microbiota Composition Is Associated with Major Infections Early after Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2020 Nov;26(11):2001-2010. doi: 10.1016/j.bbmt.2020.07.023. Epub 2020 Jul 24. PubMed PMID: 32717434.
Farhadfar N, Hsu JW, Logan BR, Sees JA, Chitphakdithai P, Sugrue MW, Abdel-Azim H, Anderlini PN, Bredeson C, Chhabra S, Diaz MA, Ganguly S, Hematti P, Kamble RT, Kasow KA, Lazarus HM, Lynch DK, Murthy HS, Olsson RF, Papari M, Przepiorka D, Savani BN, Schears R, Seo S, Solh MM, Spitzer T, Yared JA, Pulsipher MA, Shah NN, Switzer GE, Confer DL, Shaw BE, Wingard JR (CTHR). Weighty choices: selecting optimal G-CSF doses for stem cell mobilization to optimize yield. Blood Adv. 2020 Feb 25;4(4):706-716. doi: 10.1182/bloodadvances.2019000923. PubMed PMID: 32092138; PubMed Central PMCID: PMC7042992.
Shen C, Sheng Y, Zhu AC, Robinson S, Jiang X, Dong L, Chen H, Su R, Yin Z, Li W, Deng X, Chen Y, Hu YC, Weng H, Huang H, Prince E, Cogle CR, Sun M, Zhang B, Chen CW, Marcucci G, He C, Qian Z, Chen J. RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020 Jul 2;27(1):64-80.e9. doi: 10.1016/j.stem.2020.04.009. Epub 2020 May 12. PubMed PMID: 32402250; PubMed Central PMCID: PMC7335338.
Sheng Y, Yu C, Liu Y, Hu C, Ma R, Lu X, Ji P, Chen J, Mizukawa B, Huang Y, Licht JD, Qian Z. FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML. Nat Commun. 2020 Feb 17;11(1):928. doi: 10.1038/s41467-020-14590-9. PubMed PMID: 32066721; PubMed Central PMCID: PMC7026046.
He Y, Zhang X, Chang J, Kim HN, Zhang P, Wang Y, Khan S, Liu X, Zhang X, Lv D, Song L, Li W, Thummuri D, Yuan Y, Wiegand JS, Ortiz YT, Budamagunta V, Elisseeff JH, Campisi J, Almeida M, Zheng G, Zhou D. Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. Nat Commun. 2020 Apr 24;11(1):1996. doi: 10.1038/s41467-020-15838-0. PubMed PMID: 32332723; PubMed Central PMCID: PMC7181703.
Çağlayan M. The ligation of pol β mismatch insertion products governs the formation of promutagenic base excision DNA repair intermediates. Nucleic Acids Res. 2020 Apr 17;48(7):3708-3721. doi: 10.1093/nar/gkaa151. PubMed PMID: 32140717; PubMed Central PMCID: PMC7144901.
Flores-Toro JA, Luo D, Gopinath A, Sarkisian MR, Campbell JJ, Charo IF, Singh R, Schall TJ, Datta M, Jain RK, Mitchell DA, Harrison JK. CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1129-1138. doi: 10.1073/pnas.1910856117. Epub 2019 Dec 26. PubMed PMID: 31879345; PubMed Central PMCID: PMC6969504.
Burton EM, Goldbach-Mansky R, Bhaduri-McIntosh S. A promiscuous inflammasome sparks replication of a common tumor virus. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1722-1730. doi: 10.1073/pnas.1919133117. Epub 2020 Jan 9. PubMed PMID: 31919284; PubMed Central PMCID: PMC6983388.
Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, Sartor RB, Gharaibeh RZ, Bultman SJ, Redinbo MR. Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7374-7381. doi: 10.1073/pnas.1918095117. Epub 2020 Mar 13. PubMed PMID: 32170007; PubMed Central PMCID: PMC7132129.
He Y, Li W, Lv D, Zhang X, Zhang X, Ortiz YT, Budamagunta V, Campisi J, Zheng G, Zhou D. Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. Aging Cell. 2020 Mar;19(3):e13117. doi: 10.1111/acel.13117. Epub 2020 Feb 16. PubMed PMID: 32064756; PubMed Central PMCID: PMC7059172.
Kluz PN, Kolb R, Xie Q, Borcherding N, Liu Q, Luo Y, Kim MC, Wang L, Zhang Y, Li W, Stipp C, Gibson-Corley KN, Zhao C, Qi HH, Bellizzi A, Tao AW, Sugg S, Weigel RJ, Zhou D, Shen X, Zhang W. Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. Oncogene. 2020 Apr;39(14):2877-2889. doi: 10.1038/s41388-020-1203-x. Epub 2020 Feb 10. PubMed PMID: 32042113; PubMed Central PMCID: PMC7127950.
Brumley DA, Gunasekera SP, Chen QY, Paul VJ, Luesch H. Discovery, Total Synthesis, and SAR of Anaenamides A and B: Anticancer Cyanobacterial Depsipeptides with a Chlorinated Pharmacophore. Org Lett. 2020 Jun 5;22(11):4235-4239. doi: 10.1021/acs.orglett.0c01281. Epub 2020 May 16. PubMed PMID: 32418432; PubMed Central PMCID: PMC7395482.
Tomkovich S, Gharaibeh RZ, Dejea CM, Pope JL, Jiang J, Winglee K, Gauthier J, Newsome RC, Yang Y, Fodor AA, Schmittgen TD, Sears CL, Jobin C. Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer. mSystems. 2020 Jan 14;5(1). pii: e00451-19. doi: 10.1128/mSystems.00451-19. PubMed PMID: 31937674; PubMed Central PMCID: PMC6967385.
Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-X(L) degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15;192:112186. doi: 10.1016/j.ejmech.2020.112186. Epub 2020 Feb 27. PubMed PMID: 32145645; PubMed Central PMCID: PMC7433031.
Zhang X, He Y, Zhang P, Budamagunta V, Lv D, Thummuri D, Yang Y, Pei J, Yuan Y, Zhou D, Zheng G. Discovery of IAP-recruiting BCL-X(L) PROTACs as potent degraders across multiple cancer cell lines. Eur J Med Chem. 2020 Aug 1;199:112397. doi: 10.1016/j.ejmech.2020.112397. Epub 2020 May 4. PubMed PMID: 32388279; PubMed Central PMCID: PMC7325632.
Chera BS, Kumar S, Shen C, Amdur R, Dagan R, Green R, Goldman E, Weiss J, Grilley-Olson J, Patel S, Zanation A, Hackman T, Blumberg J, Patel S, Thorp B, Weissler M, Yarbrough W, Sheets N, Mendenhall W, Tan XM, Gupta GP. Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer. J Clin Oncol. 2020 Apr 1;38(10):1050-1058. doi: 10.1200/JCO.19.02444. Epub 2020 Feb 4. Erratum in: J Clin Oncol. 2020 Oct 20;38(30):3579. PubMed PMID: 32017652; PubMed Central PMCID: PMC7106982.
Frey TR, Brathwaite J, Li X, Burgula S, Akinyemi IA, Agarwal S, Burton EM, Ljungman M, McIntosh MT, Bhaduri-McIntosh S. Nascent Transcriptomics Reveal Cellular Prolytic Factors Upregulated Upstream of the Latent-to-Lytic Switch Protein of Epstein-Barr Virus. J Virol. 2020 Mar 17;94(7). pii: e01966-19. doi: 10.1128/JVI.01966-19. Print 2020 Mar 17. PubMed PMID: 31941784; PubMed Central PMCID: PMC7081890.
Tamashunas AC, Tocco VJ, Matthews J, Zhang Q, Atanasova KR, Paschall L, Pathak S, Ratnayake R, Stephens AD, Luesch H, Licht JD, Lele TP. High-throughput gene screen reveals modulators of nuclear shape. Mol Biol Cell. 2020 Jun 15;31(13):1392-1402. doi: 10.1091/mbc.E19-09-0520. Epub 2020 Apr 22. PubMed PMID: 32320319; PubMed Central PMCID: PMC7353136.
Al-Awadhi FH, Salvador-Reyes LA, Elsadek LA, Ratnayake R, Chen QY, Luesch H. Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases. ACS Chem Neurosci. 2020 Jul 1;11(13):1937-1943. doi: 10.1021/acschemneuro.0c00093. Epub 2020 Jun 19. PubMed PMID: 32559056; PubMed Central PMCID: PMC7390227.
Liu APY, Gudenas B, Lin T, Orr BA, Klimo P Jr, Kumar R, Bouffet E, Gururangan S, Crawford JR, Kellie SJ, Chintagumpala M, Fisher MJ, Bowers DC, Hassall T, Indelicato DJ, Onar-Thomas A, Ellison DW, Boop FA, Merchant TE, Robinson GW, Northcott PA, Gajjar A. Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials. Acta Neuropathol. 2020 Feb;139(2):259-271. doi: 10.1007/s00401-019-02106-9. Epub 2019 Dec 4. Erratum in: Acta Neuropathol. 2019 Dec 21;:. PubMed PMID: 31802236; PubMed Central PMCID: PMC7065912.
Gay L, Renne R. Human Cytomegalovirus Latency and Myelosuppression: A microRNA-Dependent Yin and Yang Regulatory Loop. Cell Host Microbe. 2020 Jan 8;27(1):8-10. doi: 10.1016/j.chom.2019.12.008. PubMed PMID: 31951824.
Haider SA, Asmaro K, Kalkanis SN, Lee IY, Bazydlo M, Nerenz DR, Salloum RG, Snyder J, Walbert T. The economic impact of glioma survivorship: The cost of care from a patient perspective. Neurology. 2020 Sep 15;95(11):e1575-e1581. doi: 10.1212/WNL.0000000000010263. Epub 2020 Jul 9. PubMed PMID: 32646959.
Bradley JA, Bellon JR. Quality of Life and Limb: Reducing Lymphedema Risk After Breast Cancer Therapy. Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):225-229. doi: 10.1016/j.ijrobp.2019.10.033. Review. PubMed PMID: 31928634.
Bradley JA, Indelicato DJ, Uezono H, Morris CG, Sandler E, de Soto H, Mailhot Vega RB, Rotondo R. Patterns of Failure in Parameningeal Alveolar Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 2020 Jun 1;107(2):325-333. doi: 10.1016/j.ijrobp.2020.01.035. Epub 2020 Feb 7. PubMed PMID: 32044412.
Vilaro MJ, Wilson-Howard DS, Griffin LN, Tavassoli F, Zalake MS, Lok BC, Modave FP, George TJ, Carek PJ, Krieger JL. Tailoring virtual human-delivered interventions: A digital intervention promoting colorectal cancer screening for Black women. Psychooncology. 2020 Dec;29(12):2048-2056. doi: 10.1002/pon.5538. Epub 2020 Sep 15. PubMed PMID: 32893399.
Wilkie DJ, Yao Y, Ezenwa MO, Suarez ML, Dyal BW, Gill A, Hipp T, Shea R, Miller J, Frank K, Nardi N, Murray M, Glendenning J, Perez J, Carrasco JD, Shuey D, Angulo V, McCurry T, Martin J, Butler A, Wang ZJ, Molokie RE. A Stepped-Wedge Randomized Controlled Trial: Effects of eHealth Interventions for Pain Control Among Adults With Cancer in Hospice. J Pain Symptom Manage. 2020 Mar;59(3):626-636. doi: 10.1016/j.jpainsymman.2019.10.028. Epub 2019 Nov 9. PubMed PMID: 31711969.
Guo Y, Bian J, Modave F, Li Q, George TJ, Prosperi M, Shenkman E. Assessing the effect of data integration on predictive ability of cancer survival models. Health Informatics J. 2020 Mar;26(1):8-20. doi: 10.1177/1460458218824692. Epub 2019 Jan 23. PubMed PMID: 30672356; PubMed Central PMCID: PMC7712491.
Licht JD. Oncogenesis by E2A-PBX1 in ALL: RUNX and more. Blood. 2020 Jul 2;136(1):3-4. doi: 10.1182/blood.2020005879. PubMed PMID: 32614960.
Dasari A, Morris VK, Allegra CJ, Atreya C, Benson AB 3rd, Boland P, Chung K, Copur MS, Corcoran RB, Deming DA, Dwyer A, Diehn M, Eng C, George TJ, Gollub MJ, Goodwin RA, Hamilton SR, Hechtman JF, Hochster H, Hong TS, Innocenti F, Iqbal A, Jacobs SA, Kennecke HF, Lee JJ, Lieu CH, Lenz HJ, Lindwasser OW, Montagut C, Odisio B, Ou FS, Porter L, Raghav K, Schrag D, Scott AJ, Shi Q, Strickler JH, Venook A, Yaeger R, Yothers G, You YN, Zell JA, Kopetz S. ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper. Nat Rev Clin Oncol. 2020 Dec;17(12):757-770. doi: 10.1038/s41571-020-0392-0. Epub 2020 Jul 6. Review. PubMed PMID: 32632268; PubMed Central PMCID: PMC7790747.
Thomas RM, Jobin C. Microbiota in pancreatic health and disease: the next frontier in microbiome research. Nat Rev Gastroenterol Hepatol. 2020 Jan;17(1):53-64. doi: 10.1038/s41575-019-0242-7. Epub 2019 Dec 6. Review. PubMed PMID: 31811279.
Luo H, Yu Q, Liu Y, Tang M, Liang M, Zhang D, Xiao TS, Wu L (MOO), Tan M, Ruan Y, Bungert J, Lu J. LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding. Sci Adv. 2020 Feb 19;6(8):eaaw4651. doi: 10.1126/sciadv.aaw4651. eCollection 2020 Feb. PubMed PMID: 32128389; PubMed Central PMCID: PMC7030924.
Zhou Y, Takacs GP, Lamba JK, Vulpe C, Cogle CR. Functional Dependency Analysis Identifies Potential Druggable Targets in Acute Myeloid Leukemia. Cancers (Basel). 2020 Dec 10;12(12). pii: E3710. doi: 10.3390/cancers12123710. PubMed PMID: 33321907; PubMed Central PMCID: PMC7764352.
Xie H, Kaye FJ, Isse K, Sun Y, Ramoth J, French DM, Flotte TJ, Luo Y, Saunders LR, Mansfield AS. Delta-Like Protein 3 Expression and Targeting in Merkel Cell Carcinoma. Oncologist. 2020 Sep;25(9):810-817. doi: 10.1634/theoncologist.2019-0877. Epub 2020 May 14. PubMed PMID: 32372416; PubMed Central PMCID: PMC7485334.
Crispen PL, Kusmartsev S. Mechanisms of immune evasion in bladder cancer. Cancer Immunol Immunother. 2020 Jan;69(1):3-14. doi: 10.1007/s00262-019-02443-4. Epub 2019 Dec 6. Review. PubMed PMID: 31811337; PubMed Central PMCID: PMC6949323.